Where Is Estrogen Produced In The Body ?
The estrogen that is naturally manufactured in a female’s body is referred to as endogenous estrogen. Estrogen is present in the female species in three forms. The primary variant is called estradiol, which is synthesized by the ovaries prior to menopause. This type of estrogen is also signified as 17-beta estradiol and E2. A relatively weaker variant of estrogen is estrone, also known as E1. This type of estrogen illustrates the primary form of the hormone present in the female body during the menopausal years.
he ovaries and fat tissue are both responsible for the production of estrone. The weakest of the 3 types of estrogen is estriol or E3. This variety of the hormone is found in the uterus along with the developing fetus and is produced by the other estrogens.
The level of estrogen in the body varies in accordance with the different stages of the menstrual cycle. While the hormone is mainly produced by the egg follicles in the ovaries; the corpus luteum and the placenta also contribute towards its synthesis. The sound production of estrogen in women is also known to be associated with two other hormones called the luteinizing hormone (LH) and the follicle stimulating hormone (FSH) during the reproductive years of life. Estrogen is manufactured in minute amounts by the liver, breasts and adrenal glands as well. These sources regarded as the secondary sources of its production are of importance in the menopausal years of a woman’s life. The fact that fat cells are also involved in the production of this hormone explains the reason for infertility amongst those women who are underweight or overweight.
Amongst the female species, the theca interna cells present in the ovaries are responsible for the production of estrogen. The process is triggered by the synthesis of androstenedione from cholesterol. Androstenedione gains entry into the adjacent granulosa cells via the basal membrane, where it is transformed into estrone or estradiol by the catalytic action of the enzyme aromatase. The conversion either takes place directly or with the aid of testosterone.
Although present in much smaller amounts, estrogen also has vital functions to perform amongst men. The hormone is produced either by the testis or the adrenal glands in this gender. The function of estrogen in men includes proper growth of the penis and the testicles, maturation of the sperm, maintenance of the sexual libido and the development of secondary sexual characteristics like growth of facial as well as body hair, deepening of the voice and formation of muscles.
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