What Is The Treatment For Testicular Cancer Relapse ?

What Is The Treatment For Testicular Cancer Relapse ?

Testicular cancer is highly curable and chemotherapy using cisplatin has been very effective and it has provided relapse free long term survival of patients with testicular germ cell tumors.

Some patients who have experienced disappearance of their cancer with initial treatment may experience a recurrence of their cancer.

Late relapse of testicular cancer has been noted. It is defined as tumor recurrence 2 years after complete remission. The incidence of such relapse is in the 2 to 6 percent of the cases. The median relapse free interval is observed to be in the range of 5.4 to 7.1 years from the initial treatment.    

The course of further treatment in case of relapse depends on factors such prior treatment, site of recurrence and individual patient consideration. The treatment consists of ifosafamide, cisplatin, and either etoposide or vinblatine. This treatment has shown good results in 25 percent of the cases. This is considered to be the standard initial salvage regime. High dose chemotherapy with autologous bone marrow transplantation has also been used in controlled cases. In a few cases where the disease is confined to a single site, surgical removal may be a better option.

There is also a suggestion that a maintenance regimen of daily oral etoposide may benefit patients to achieve complete remission after salvage therapy. In case of relapse more than 2 years after achieving complete remission, chemotherapy is not found to be effective. Surgical treatment is considered to be more effective if technically feasible. Teratoma also is known to be treatable with surgery.

More Articles :

What Is The Treatment For Testicular Cancer Relapse