Age-related cataracts are the leading cause of visual disability in the U.S. and other developed countries. Cataract is a cloudy or opaque area in the normally transparent lens of the eye.
As the lens continues to change, several specific symptoms including blurred vision; sensitivity to light and glare; increased nearsightedness; or distorted images in either eye, may develop.
Research has focused on the role of nutritional antioxidants because of evidence that light-induced oxidative damage of lens proteins may lead to the development of age-related cataracts. Vitamin B2 (Riboflvin) being a great nutritional anti-oxidant has been the preferred anti-oxidant for many studies.
A few studies have been discussed here:
- A case-control study found significantly decreased risk of age-related cataract (33 percent to 51 percent) in men and women in the highest quintile (one fifth of a sample or population) of dietary riboflavin intake (median of 1.6 to 2.2 mg/day) compared to those in the lowest quintile (median of 0.08 mg/day in both men and women).
- Another case-control study reported that individuals in the highest quintile of riboflavin nutritional status had approximately one half the occurrence of age-related cataract as those in the lowest quintile of riboflavin status.
- A cross-sectional study of 2,900 Australian men and women, 49 years of age and older, found that those in the highest quintile of riboflavin intake were 50 percent less likely to have cataracts than those in the lowest quintile.
These observational studies provide support for the role of dietary and supplemental vitamin B2 in the prevention of cataracts. However, placebo-controlled intervention trials are needed to confirm the relationship between Riboflavin and cataract.
More Articles :